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Image Search Results
Journal: American Journal of Physiology - Lung Cellular and Molecular Physiology
Article Title: Moderate oxygen augments lipopolysaccharide-induced lung injury in mice
doi: 10.1152/ajplung.00308.2009
Figure Lengend Snippet: Neutrophil depletion abrogates the augmentation of LPS-induced lung injury by supplemental oxygen. Mice received LPS and supplemental oxygen as described, as well as concomitant treatment with neutrophil-depleting Gr-1 or isotype antibodies. Injury parameters were assessed at day 4. A: BAL neutrophils and macrophages were quantified (n = 3–5/group, *P < 0.05). B: representative lung histology sections from each group, stained with H&E. C: lung injury scores as described for each group; n = 3–5 mice/group; *P < 0.05. BAL protein and albumin (D) and wet lung to body weight (E) were in each group (n = 3–5/group, *P < 0.05). TNFα (F) and chemokines MIP-2 and KC (G) were assessed in BAL fluid of mice from each group (n = 3–5/group; *P < 0.05).
Article Snippet: Mice were administered intraperitoneal (IP) injections of
Techniques: Staining